Global Ideas: A Danish stock that will ‘knock your socks off’

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How should a UK-based contrarian investor approach picking global stocks? Perhaps they simply ignore them. After all, as institutional allocations to the domestic stock market dwindle, the herd-defying strategy might be to double down on Blighty.

Then again, if the definition of a contrarian is someone who thinks independently, then there’s no reason they should treat global stocks any differently.

Being a contrarian has less to do with categorisation than weighing the evidence – the positives, the negatives and the unknowns – to understand where the herd will eventually go. It’s why a contrarian approach is often synonymous with value investing, and a more thorough process than just following the news. And as I’ve remarked before, the rigour of rules-based investing might be its own sort of contrarianism.

To return to our question, then, how might a contrarian value investor approach global stocks? The simple answer is that for all the extra scrutiny, resources, hype and capital flows involved with internationally significant businesses, even giants fall in and out of favour. And where there are swings in sentiment, there are always opportunities.

For the second in our new Global Ideas series, we’re putting the constituents of the MSCI All-World index through our Contrarian Value screen. While last week’s strategy rounded on a promising Chinese electric vehicle maker, our Ken Fisher-inspired screen focuses on a different kind of EV – the enterprise value – to identify lowly-rated stocks with otherwise quality attributes.

When applied to the UK, this approach has been a winner, producing a five-year total return of 108 per cent, versus 67 per cent from the FTSE All-Share. In its 14-year history, a period in which value investing was largely out of favour, the headline return was also a very healthy 413 per cent, against 159 per cent from the index.

The original screen first selects stocks with a solid mix of past and projected sales growth, profitability, gearing and cash generation, and then ranks the results by the lowest EV (market capitalisation plus debt, minus cash) to sales (EV/sales ratio), as a secondary check for cheapness. In full, here are those tests:

■ Five-year compound average annual sales growth rate of 7 per cent or more

■ Forecast sales growth in each of the next two years

■ An average operating profit margin of at least 10 per cent over the past five years

■ Positive free cash flow

■ Gearing (net debt as a percentage of net assets) of less than 50 per cent, or net debt of less than two times cash profit.

A few issues crop up when applied to a 2,200-strong list of global blue-chips. For one, hundreds of stocks meet the criteria. Unfortunately, if we were then to only select the cheapest, we would be left with an array of obscure, largely untradeable stocks with slightly wobbly data assumptions.

To get around these obstacles, I’ve introduced a ranking criteria based on a score that combines the lowest EV/sales ratios and the first three tests. Once this is applied, the screen is then ranked by EV/sales, and filtered once more to remove UK stocks and shares in markets it is very hard or near-impossible for retail investors to trade.

GMAB:CPH

Genmab A/S

1mth

Today change

+3.00%

Price (DKK)

1493.00

The table below shows the top 15 MSCI All-World constituents that meet the criteria. I’ll let you decide what the high representation of resources stocks – including a trio of unloved North American oil and gas stocks, and four precious metals miners – says about the results. Clearly, recorded and forecast sales growth takes on a different meaning when volatile commodity prices play such a large role.

Name Ticker Exchange Mkt Cap Fwd PE DY EV/Sales 5yr sales CAGR 5yr av EBIT % 2yr Fwd av sales FY EPS gr+1 FY EPS gr+2 12M Fwd EPS change 3-mth Mom
Anglogold Ashanti AU NYSE £17.8bn 8 2.0% 2.2 10.4% 22.4% 31.5% 149.9% 6.0% 77.8% 7.1%
LPL Financial LPLA NASDAQ £21.9bn 17 0.3% 2.3 17.1% 13.9% 21.9% 14.1% 23.2% 13.4% 15.6%
Gold Fields GFIOF JSE £16.3bn 8 2.4% 2.8 17.3% 33.5% 28.4% 107.7% 18.3% 83.0% 2.8%
James Hardie Industries JHIUF ASX £8.6bn 18 2.9 9.2% 21.7% 23.8% -7.9% 16.7% -13.5% -11.4%
ANTA Sports Products ANPDF Hong Kong £24.0bn 18 2.5% 3.0 14.8% 20.5% 11.7% -9.3% 12.9% 5.6% 21.6%
ARC Resources AETUF Toronto £8.7bn 9 2.7% 3.3 33.2% 25.2% 11.6% 41.9% 20.5% 14.9% 8.4%
Genmab GNMSF Copenhagen £10.1bn 13 3.5 32.0% 42.6% 10.7% -19.2% 18.7% 23.0% 10.5%
Wuxi Biologics WXIBF Hong Kong £10.6bn 22 3.6 35.0% 26.3% 15.3% 25.0% 18.1% 7.7% 16.2%
Tokyo Electron TOELF Tokyo £64.8bn 21 2.3% 3.6 16.6% 25.9% 7.9% 2.3% 15.9% 19.1% 29.3%
Coterra Energy CTRA NYSE £14.0bn 8 3.6% 3.8 22.4% 38.0% 24.3% 62.7% 19.9% 14.7% -3.8%
M3 MTHRF Tokyo £6.2bn 26 1.2% 3.8 16.8% 28.7% 18.5% 15.5% 11.8% 3.7% 28.3%
Tourmaline Oil TRMLF Toronto £13.1bn 11 2.5% 4.2 19.9% 32.0% 15.7% 28.7% 41.7% -7.7% 2.7%
Agnico Eagle Mines AEM Toronto £44.9bn 17 1.4% 4.8 27.9% 26.9% 14.3% 60.1% 7.0% 85.8% -2.4%
United Therapeutics UTHR NASDAQ £9.9bn 10 4.9 14.7% 45.7% 9.3% 13.2% 5.3% 4.0% 1.8%
Alamos Gold AGI Toronto £8.3bn 16 0.4% 5.6 15.3% 27.1% 24.2% 67.7% 33.8% 81.9% -15.3%
Source: FactSet. Converted to £, as of 17 July 2025.

Another theme is biotech. In this small cluster, you’ll find United Therapeutics (US:UTHR), a Nasdaq-listed drug developer focused on rare disease, end-stage lung disease and organ transplantation, and Hong Kong-listed WuXi Biologics (HK:2269), a drug discovery company that had a mammoth 66 projects in late-phase clinical trials at the end of 2024.

Then there’s Genmab (DK:GMAB), which has the highest combined four-test score in the table after Gold Fields (SA:GFI) and Corterra Energy (US:CTRA).

Founded in 1998, Genmab develops customised antibodies for use in cancer treatments. Historically, the group has licensed its technology and the commercialisation of its drugs to large pharma giants including Novartis (CH:NOVN), Amgen (US:AMGN) and GSK (GSK), but in recent years has branched out into product development.  

It is one of Denmark’s largest public companies, albeit lesser known than either Wegovy manufacturer (and the Copenhagen exchange’s undisputed 1,000-pound gorilla) Novo Nordisk (DK:NOVO.B), or fellow biotech blue-chip Novonesis (DK:NSIS.B), which was spun out of Novo in 2000 and merged with Chr. Hansen in 2024.

Given its pedigree and peer grouping, you might wonder why Genmab’s EV/sales multiple, which falls to just 2.6 on consensus forecasts for 2026, reflects such apparently low expectations.

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To understand, let’s first look at the numerator. Because the enterprise value excludes a company’s net cash position – which in Genmab’s case stands at DKr22.3bn (£2.5bn) – the knowhow, patents, royalty agreements and operating company, together with all other assets and liabilities are being valued at just £7.8bn.

As for the denominator, sales are also strong, at least for now. This year, executives have guided for revenue to land between $3.3bn (£2.5bn) and $3.7bn. At the midpoint, this includes a 15 per cent rise in royalty payments to $2.9bn and a 39 per cent jump in direct drug sales to $438mn, offsetting a 44 per cent dip in milestone and reimbursement payments to $162mn.

Until 2028, the top line is expected to push higher amid growing sales of its two products: lymphoma treatment Epkinly (which it co-developed with AbbVie (US:ABBV)) and recently approved cervical cancer medicine Tivdak (profits from which it shares with Pfizer (US:PFE) following the latter’s acquisition of co-developer Seagen in 2023).

Thereafter the picture gets cloudier, as exclusivity on its blockbuster Darzalex starts to end. As far as patent cliffs go, this is a steep one. Royalties from the blood cancer treatment, which Genmab originally developed but which is licensed by Johnson & Johnson (US:JNJ), amounted to 64 per cent of the cumulative top line from 2020 to 2024, and are expected to generate three-fifths of sales between 2025 and 2028, per FactSet. But by 2032, this huge revenue stream will have run dry.

The investment case wasn’t always defined by such precarity. Rewind the clock to early 2021, when the potential for Darzalex was emerging, the group had just inked a long-term oncology collaboration with AbbVie, and shares in the sector were boosted by Covid-19 vaccine success, and Genmab shares traded above 60 times forward earnings. That multiple has since collapsed beneath the level of its major international partners.

However, this derating masks the options available. Currently, consensus forecasts are that the group lets the Darzalex royalties accrue, resulting in net cash tripling to £7.7bn and shareholder equity more than doubling to £9.3bn by 2029. While this seems unlikely, given Genmab’s stated aim to both develop its pipeline and “expand… through inorganic opportunities”, it suggests the market sees little value beyond existing cash and a single (though admittedly large) royalty stream.  

Given the company’s record of development, that seems an oversight. A push to transform the lives of cancer sufferers by 2030 with its peculiarly trademarked “Knock-Your-Socks-Off” antibody medicines now centres on three candidates that have each entered phase 3 clinical trials.

First is the expanded clinical use of epcoritamab, the bispecific antibody in Epkinly developed with AbbVie. Second is acasunlimab, a technology used to treat non-small-cell lung cancers, over which Genmab assumed full developmental control in 2024 following the exit of its partner BioNTech (US:BNTX). Third is ovarian cancer treatment candidate Rina-S, which Genmab acquired through its purchase of ProfoundBio in 2024.

Of course, drug discovery, commercialisation and associated liabilities present myriad risks. But even if Genmab’s candidates all fail – which seems unlikely, given several are expansions of existing therapies – then investors have a decent degree of downside protection. And if its leading trial candidates prove more successful, then who knows? Given the shares’ rating, a small run of success may be all that’s required to tempt a bigger US beast to swoop on what is clearly a highly competent science team.

After all, even the bigger, more richly valued players have their own patent cliffs to address.  

Several platforms, including Hargreaves Lansdown and II, offer Genmab’s Nasdaq-listed American depositary receipts (US:GMAB, ISIN US3723032062). Hargreaves also offers the Copenhagen-listed shares (DK:GMAB, ISIN DK0010272202) and says either class can be held in an Isa, Lifetime Isa, Sipp or general investment account. Consult with your broker or investment platform for further information.