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Sifting through countless of stocks in the Biotechnology industry can be tedious, and sometimes two stocks are just too similar to judge which is the better investment. If you’re on the fence about investing in Sarepta Therapeutics, Inc. or Immunocore Holdings plc because you’re not sure how they measure up, it’s important to compare them on a few factors before making your decision.
Read on to learn how Sarepta Therapeutics, Inc. and Immunocore Holdings plc compare based on key financial metrics to determine which better meets your investment needs.
About Sarepta Therapeutics, Inc. and Immunocore Holdings plc
Sarepta Therapeutics, Inc., a commercial-stage biopharmaceutical company, focuses on the discovery and development of RNA-targeted therapeutics, gene therapies, and other genetic therapeutic modalities for the treatment of rare diseases. It offers EXONDYS 51 injection to treat Duchenne muscular dystrophy (Duchenne) in patients with confirmed mutation of the dystrophin gene that is amenable to exon 51 skipping; VYONDYS 53 for the treatment of Duchenne in patients with confirmed mutation of the dystrophin gene that is amenable to exon 53 skipping; AMONDYS 45 for the treatment of Duchenne in patients with confirmed mutation of the dystrophin gene that is amenable to exon 45 skipping; and ELEVIDYS, an adeno-associated virus based gene therapy for the treatment of ambulatory pediatric patients with Duchenne with a confirmed mutation in the Duchenne gene. The company is also developing SRP-9003, a limb-girdle muscular dystrophies gene therapy program. It has collaboration and license agreements with F. Hoffman-La Roche Ltd; Arrowhead Pharmaceuticals, Inc.; University of Western Australia; Catalent Maryland, Inc.; Nationwide Children’s Hospital; Dyno Therapeutics; Hansa Biopharma; Duke University; and Genethon. The company was incorporated in 1980 and is headquartered in Cambridge, Massachusetts.
Immunocore Holdings plc, a commercial-stage biotechnology company, engages in the development of immunotherapies for the treatment of cancer, infectious, and autoimmune diseases. The company offers KIMMTRAK for the treatment of patients with unresectable or metastatic uveal melanoma. It also develops other programs for oncology, including tebentafusp that is in Phase 3 clinical trial to treat advanced cutaneous melanoma and adjuvant uveal melanoma; and brenetafusp that is in Phase 3 clinical trial to treat first-line advanced cutaneous melanoma and in a Phase 1/2 clinical trial in multiple tumor types. In addition, the company’s products under development include IMC-R117C (PIWIL-1) that is in Phase 1/2 clinical trial for the treatment of advanced solid tumors, including colorectal cancer; IMC-P115C (PRAME-HLE-A02) that is in Phase 1 clinical trial for patients with tumors that express PRAME; IMC-M113V that is in Phase 1 clinical trials for a potential functional cure in human immunodeficiency virus (HIV); and IMC-I109V that is in Phase 1 clinical trials for a potential functional cure in hepatitis B virus (HBV). Further, it develops IMC-T119C, which is in preclinical trial for multiple solid tumor cancers; IMC-S118AI to treat type 1 diabetes; and IMC-U120AI to treat atopic dermatitis. Immunocore Holdings plc was founded in 1999 and is headquartered in Abingdon, the United Kingdom.
Latest Biotechnology and Sarepta Therapeutics, Inc., Immunocore Holdings plc Stock News
As of November 26, 2025, Sarepta Therapeutics, Inc. had a $2.2 billion market capitalization, compared to the Biotechnology median of $220.1 million. Sarepta Therapeutics, Inc.’s stock is down 82.8% in 2025, up 27.8% in the previous five trading days and down 81.66% in the past year.
Currently, Sarepta Therapeutics, Inc. does not have a price-earnings ratio. Sarepta Therapeutics, Inc.’s trailing 12-month revenue is $2.4 billion with a -11.2% net profit margin. Year-over-year quarterly sales growth most recently was -14.5%. Analysts expect adjusted earnings to reach $-2.013 per share for the current fiscal year. Sarepta Therapeutics, Inc. does not currently pay a dividend.
As of November 26, 2025, Immunocore Holdings plc had a $2.0 billion market cap, putting it in the 56th percentile of all stocks. Immunocore Holdings plc’s stock is up 36% in 2025, up 3.8% in the previous five trading days and up 24.32% in the past year.
Currently, Immunocore Holdings plc does not have a price-earnings ratio. Immunocore Holdings plc’s trailing 12-month revenue is $379.6 million with a -7.7% net profit margin. Year-over-year quarterly sales growth most recently was 29.3%. There are no analysts providing consensus earnings estimates for the current fiscal year. Immunocore Holdings plc does not currently pay a dividend.
How We Compare Sarepta Therapeutics, Inc. and Immunocore Holdings plc Stock Grades
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AAII’s proprietary stock grades come with A+ Investor. These offer intuitive A‐F grades for each of five key investing factors: value, growth, momentum, earnings estimate revisions and quality. Here, we’ll take a closer look at Sarepta Therapeutics, Inc. and Immunocore Holdings plc’s stock grades to see how they measure up against one another.
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